automated patch-clamp system Search Results


automated patch-clamp system  (Nanion Technologies GmbH)
90
Nanion Technologies GmbH automated patch-clamp system
Automated Patch Clamp System, supplied by Nanion Technologies GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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patchliner automated patch-clamp system  (Nanion Technologies GmbH)
90
Nanion Technologies GmbH patchliner automated patch-clamp system
Patchliner Automated Patch Clamp System, supplied by Nanion Technologies GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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automated patch clamp platforms  (Chantest Inc)
90
Chantest Inc automated patch clamp platforms
Automated Patch Clamp Platforms, supplied by Chantest Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
automated patch clamp platforms - by Bioz Stars, 2026-04
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automated patch clamp qpatch  (Biolin Scientific)
90
Biolin Scientific automated patch clamp qpatch
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Automated Patch Clamp Qpatch, supplied by Biolin Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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cytopatch automated patchclamp platform  (Cytocentrics Bioscience GmbH)
90
Cytocentrics Bioscience GmbH cytopatch automated patchclamp platform
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Cytopatch Automated Patchclamp Platform, supplied by Cytocentrics Bioscience GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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flyscreen® 8500 automated patch clamp  (Flyion GmbH)
90
Flyion GmbH flyscreen® 8500 automated patch clamp
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Flyscreen® 8500 Automated Patch Clamp, supplied by Flyion GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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automated patch-clamp robot synchropatch 384  (Nanion Technologies GmbH)
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Nanion Technologies GmbH automated patch-clamp robot synchropatch 384
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Automated Patch Clamp Robot Synchropatch 384, supplied by Nanion Technologies GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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four-channel medium throughput fully automated patch-clamp system patchliner  (Nanion Technologies GmbH)
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Nanion Technologies GmbH four-channel medium throughput fully automated patch-clamp system patchliner
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Four Channel Medium Throughput Fully Automated Patch Clamp System Patchliner, supplied by Nanion Technologies GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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automated patch clamp  (Sophion Bioscience)
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Sophion Bioscience automated patch clamp
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Automated Patch Clamp, supplied by Sophion Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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automated patch-clamp assays  (SB Drug Discovery)
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SB Drug Discovery automated patch-clamp assays
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Automated Patch Clamp Assays, supplied by SB Drug Discovery, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cube automated patch-clamp  (Sophion Bioscience)
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Sophion Bioscience cube automated patch-clamp
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Cube Automated Patch Clamp, supplied by Sophion Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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automated patch-clamp recordings  (Sanofi)
90
Sanofi automated patch-clamp recordings
Small-conductance Ca 2+ -activated K+ channel inhibitors <t>AP14145</t> (left) and NS8593 (right).
Automated Patch Clamp Recordings, supplied by Sanofi, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Small-conductance Ca 2+ -activated K+ channel inhibitors AP14145 (left) and NS8593 (right).

Journal: Circulation. Arrhythmia and Electrophysiology

Article Title: Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca 2+ -Activated K + Channels in Pigs

doi: 10.1161/CIRCEP.117.005125

Figure Lengend Snippet: Small-conductance Ca 2+ -activated K+ channel inhibitors AP14145 (left) and NS8593 (right).

Article Snippet: Effects of AP14145 on hSK3 (KCa2.3) and hERG (hKV11.1) were investigated by automated patch clamp (Qpatch; Biolin Scientific, Sophion, Denmark) as previously described.

Techniques:

Effect of AP14145 on heterologous expressed ion channels. Left , Concentration response curves of AP14145 effects on hSK3 (n=11), hERG (n=5), and K ir 3.1/K ir 3.4 (n=6). Middle , % Inhibition of K V 7.1/KCNE1 (n=9), K ir 2.1 (n=5), K V 1.5 (n=5), and K V 4.3/KChiP2 (n=5) by 30 µmol/L AP14145 and on Na V 1.5 by 15 µmol/L AP14145 (n=3). Right , % Inhibition of hCa V 1.2 by dimethyl sulfoxide (n=3) or AP14145 by 10 and 30 µmol/L (n=6). hERG, NaV1.5, CaV1.2, and SK3 are measured by automated patch clamping and the remaining by 2-electrode voltage-clamp.

Journal: Circulation. Arrhythmia and Electrophysiology

Article Title: Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca 2+ -Activated K + Channels in Pigs

doi: 10.1161/CIRCEP.117.005125

Figure Lengend Snippet: Effect of AP14145 on heterologous expressed ion channels. Left , Concentration response curves of AP14145 effects on hSK3 (n=11), hERG (n=5), and K ir 3.1/K ir 3.4 (n=6). Middle , % Inhibition of K V 7.1/KCNE1 (n=9), K ir 2.1 (n=5), K V 1.5 (n=5), and K V 4.3/KChiP2 (n=5) by 30 µmol/L AP14145 and on Na V 1.5 by 15 µmol/L AP14145 (n=3). Right , % Inhibition of hCa V 1.2 by dimethyl sulfoxide (n=3) or AP14145 by 10 and 30 µmol/L (n=6). hERG, NaV1.5, CaV1.2, and SK3 are measured by automated patch clamping and the remaining by 2-electrode voltage-clamp.

Article Snippet: Effects of AP14145 on hSK3 (KCa2.3) and hERG (hKV11.1) were investigated by automated patch clamp (Qpatch; Biolin Scientific, Sophion, Denmark) as previously described.

Techniques: Concentration Assay, Inhibition

Plasma concentrations of AP14145 in pig. Left , Measured total plasma concentration of AP14145 in pigs after bolus injection of 5 mg/kg AP14145 fitted with an exponential 1-phase decay model. Right , Calculated free plasma concentration of AP14145 based on a plasma protein binding of 88% after 3 injections of 5, 8, and 8 mg/kg of AP14145 with 30-min intervals.

Journal: Circulation. Arrhythmia and Electrophysiology

Article Title: Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca 2+ -Activated K + Channels in Pigs

doi: 10.1161/CIRCEP.117.005125

Figure Lengend Snippet: Plasma concentrations of AP14145 in pig. Left , Measured total plasma concentration of AP14145 in pigs after bolus injection of 5 mg/kg AP14145 fitted with an exponential 1-phase decay model. Right , Calculated free plasma concentration of AP14145 based on a plasma protein binding of 88% after 3 injections of 5, 8, and 8 mg/kg of AP14145 with 30-min intervals.

Article Snippet: Effects of AP14145 on hSK3 (KCa2.3) and hERG (hKV11.1) were investigated by automated patch clamp (Qpatch; Biolin Scientific, Sophion, Denmark) as previously described.

Techniques: Clinical Proteomics, Concentration Assay, Injection, Protein Binding

Effects of vernakalant and AP14145 on left atrial (LA) effective refractory period (ERP), atrial fibrillation (AF) duration, and left ventricle (LV) ERP. Top , Effects in control pigs. Bottom , Effects in 1-wk atrial tachypacing pigs.

Journal: Circulation. Arrhythmia and Electrophysiology

Article Title: Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca 2+ -Activated K + Channels in Pigs

doi: 10.1161/CIRCEP.117.005125

Figure Lengend Snippet: Effects of vernakalant and AP14145 on left atrial (LA) effective refractory period (ERP), atrial fibrillation (AF) duration, and left ventricle (LV) ERP. Top , Effects in control pigs. Bottom , Effects in 1-wk atrial tachypacing pigs.

Article Snippet: Effects of AP14145 on hSK3 (KCa2.3) and hERG (hKV11.1) were investigated by automated patch clamp (Qpatch; Biolin Scientific, Sophion, Denmark) as previously described.

Techniques: Control

Cardioversion and protection against rei nduction of vernakalant -resistant atrial fibrillation (AF) with AP14145. Left , Increasing doses of AP14145 cardioverts vernakalant-resistant AF and protects against reinduction of AF in 8 of 8 vernakalant-resistant AF pigs. Right , Time to cardioversion of AF by increasing doses of AP14145 in vernakalant-resistant AF pigs.

Journal: Circulation. Arrhythmia and Electrophysiology

Article Title: Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca 2+ -Activated K + Channels in Pigs

doi: 10.1161/CIRCEP.117.005125

Figure Lengend Snippet: Cardioversion and protection against rei nduction of vernakalant -resistant atrial fibrillation (AF) with AP14145. Left , Increasing doses of AP14145 cardioverts vernakalant-resistant AF and protects against reinduction of AF in 8 of 8 vernakalant-resistant AF pigs. Right , Time to cardioversion of AF by increasing doses of AP14145 in vernakalant-resistant AF pigs.

Article Snippet: Effects of AP14145 on hSK3 (KCa2.3) and hERG (hKV11.1) were investigated by automated patch clamp (Qpatch; Biolin Scientific, Sophion, Denmark) as previously described.

Techniques: